Extra-Corporeal Membrane Oxygenation (ECMO) Therapy

As a recognized leader in critical care training, Cooper University Health Care is home to South Jersey’s first and only formal extracorporeal membrane oxygenation (ECMO) program, giving the region’s residents access to this lifesaving therapy closer to home.

ECMO is an advanced therapy used to support patients with severe lung failure or critical heart-lung conditions. At Cooper, ECMO is used in the Intensive Care Unit (ICU) to temporarily take over the function of the lungs so they can rest or heal.

ECMO does not cure the underlying condition but provides time for recovery by delivering oxygen to the blood and removing carbon dioxide when the lungs cannot.

Who May Benefit From ECMO?

A patient may be a candidate for ECMO if they have a condition that is potentially reversible and treatable and has not improved with other treatments. Some common conditions that may benefit from ECMO are:

• Acute respiratory distress syndrome (ARDS)
• Severe pneumonia or influenza
• Conditions causing severe heart failure
• Pulmonary embolism
• Severe asthma
• Complications after heart surgery

How ECMO Works

ECMO uses tubes called cannulas placed into large blood vessels to circulate the patient’s blood through a machine outside of the body (called an ECMO circuit). ECMO works by removing blood from a large vein (through a cannula) and sending that blood through the ECMO circuit. This circuit pumps the blood through an oxygenator, which functions like a patient’s healthy lung. The oxygenator adds oxygen to the blood and remove carbon dioxide (CO2). The blood is warmed and then returned to the patient’s body through another cannula.

In some patients, the cannula draining blood is in the groin and the cannula returning blood to the patient is in a vein in the neck (see diagram).

In others, a single cannula with two openings may be used. One opening drains blood and the other allows blood to return to the patient after passing through the ECMO machine.

How Long Do Patients Require ECMO?

The amount of time a patient remains on ECMO depends on the underlying medical condition and the rate of recovery. As patients improve, ECMO support is gradually reduced for short periods in a process called weaning. This will allow the ECMO team to see how the lungs are recovering.

When no longer needed, the ECMO machine is turned off and the cannulas are removed, either in the ICU or in the operating room, depending on the patient’s needs.

A Comprehensive ECMO Care Team

Providing ECMO therapy requires a highly coordinated, multidisciplinary team of specialists committed to delivering academic-level critical care. The Cooper team includes:

• Intensive care physicians
• ECMO physicians
• Cardiothoracic surgeon and/or cardiologist
• ECMO perfusionist
• Critical care nurses
• Respiratory therapists
• Pharmacists
• Social workers
• Dieticians
• Physical therapists
• Other sub-specialists including infectious disease, pulmonary, nephrology, and others as needed for optimal care
• Spiritual support

Mobile Extracorporeal Membrane Oxygenation (ECMO) Transport Program

Expanding access to advanced life support for patients experiencing life‑threatening heart or lung failure — before they ever reach the hospital.

Developed by Cooper’s Center for Critical Care Services in collaboration with the Cooper Transfer Center, Cooper EMS, and Cooper’s Level 1 Trauma Program, the initiative enables a specialized team to travel to referring hospitals, initiate ECMO at the bedside, stabilize critically ill patients, and safely transport them back to Cooper for ongoing management.

What Mobile ECMO Means for Patients

ECMO is an advanced form of life support used when the heart or lungs can no longer function adequately on their own, such as in cases of severe cardiac failure, acute respiratory distress syndrome (ARDS), or refractory respiratory failure. By circulating and oxygenating blood outside the body, ECMO allows these organs to rest and recover when conventional therapies are no longer enough.

With mobile capability, Cooper can now:

• Deploy a highly trained ECMO retrieval team directly to outside hospitals
• Perform bedside cannulation and initiate veno‑venous (VV) ECMO
• Stabilize patients who are too unstable for traditional transport
• Provide rapid, coordinated transfer to Cooper for continued critical care

This level of mobile ECMO support is a hallmark of leading quaternary care centers and represents a major advancement for patients across South Jersey and the region.

A Multidisciplinary Team Built for High‑Acuity Care

Cooper’s Mobile ECMO Transport Program brings together experts from across the health system, including:

• Critical care physicians
• Advanced practice providers
• Perfusion specialists
• Critical care nurses
• Cooper EMS and critical care transport professionals
• Trauma and emergency response teams

This seamless collaboration ensures rapid consultation, team mobilization, bedside initiation of ECMO, and safe transport — all coordinated through the Cooper Transfer Center.