Genicular Artery Embolization

Genicular artery embolization (GAE) is an innovative, minimally invasive procedure that can help reduce chronic knee pain caused by osteoarthritis (OA). The interventional radiology specialists at Cooper University Health Care perform GAE using advanced imaging to target blood vessels in the knee that cause inflammation, offering an effective alternative to surgery.

For many patients, GAE is a safe, effective alternative to knee replacement and provides meaningful pain relief and improved mobility, helping them return to their daily activities without the downtime of traditional surgery. Cooper is among the only centers in the region offering this cutting-edge treatment.

Who May Benefit From GAE

GAE may be an option for patients who:

• Have moderate to severe knee pain caused by osteoarthritis, or continued pain after knee replacement
• Continue to have pain despite medications, physical therapy, or joint injections
•  Are not ready or not eligible for knee replacement surgery
• Prefer a non-surgical treatment option with a shorter recovery time

Advantages of GAE

Compared with surgical or joint replacement procedures, GAE offers several benefits:

• Minimally invasive, same-day procedure, with no hospital stay required
• Minimal to no pain during or after the procedure
• No general anesthesia required – performed under mild, or “twilight,” sedation
• Faster recovery and return to daily activities
• High success rates in reduced inflammation and significant pain relief, which may last months or longer

What to Expect During the Procedure

During the procedure, an interventional radiologist makes a small pinhole in the skin at the upper thigh or wrist. Using X-ray guidance, a thin, flexible tube called a catheter is carefully threaded through an artery to the blood vessels that supply the inflamed lining of the knee (the synovium).

Tiny particles are then released through the catheter to block these small arteries, reducing excess blood flow to the synovium. This decrease in blood flow helps calm inflammation, which can relieve pain, reduce swelling, and improve movement.

The procedure typically takes one to two hours and is performed under mild sedation, allowing you to remain relaxed and comfortable throughout.

Recovery and Results

Because GAE is performed as an outpatient procedure, most patients go home the same day. Afterward, you may experience:

• Mild soreness or bruising at the catheter site
• Gradual improvement in knee pain over several days to weeks as inflammation decreases
• Long-lasting relief that can improve quality of life and mobility

Some patients begin noticing improvement as early as one to two weeks after the procedure, with continued progress over the following months.

Why Choose Cooper for GAE?

Cooper is a regional leader in advanced interventional radiology treatments, providing patients access to the latest minimally invasive options. Our board-certified interventional radiologists use cutting-edge, image-guided technology to deliver safe and effective care tailored to each patient’s needs.