Peroral Endoscopic Myotomy

Peroral endoscopic myotomy (POEM) is a minimally invasive procedure used to treat muscle disorders in the esophagus that can cause swallowing problems. 

POEM is the primary treatment approach for a rare condition called achalasia, in which thickness in the sphincter connecting the esophagus and stomach that makes it difficult for food and liquids to pass into the stomach. The procedure may also be used to treat spasms and other disorders in the esophagus that have not responded to other treatments. 

A specific kind of POEM procedure, called a gastric peroral endoscopic myotomy (G-POEM,) is used to treat those living with a condition in which the stomach does not empty completely. The condition, called gastroparesis, may develop if there is damage to the vagus nerve that controls the movement of food in the digestive tract or if the nerve stops working.

Preparing for a POEM 

Your stomach must be empty in advance of your gastroenterologist performing a POEM or G-POEM. You may need to be on a liquid diet and fasting in advance of your procedure.

You’ll receive clear, specific instructions from your doctor ahead of time, so you know exactly what to do to prepare for your peroral endoscopic myotomy.

During the Procedure

A POEM typically takes about one hour to perform and a G-POEM can take up about 90 minutes. During the procedure, an advanced intervention gastroenterologist inserts a long, flexible tube called an endoscope into the mouth and down through the esophagus. Your gastroenterologist will then help the muscles in the lower part of the esophagus relax by making small cuts in the tissue. Making the muscles relax allows food and liquids to pass more easily to the stomach.

Will There Be Side Effects Afterward?

Although rare, the potential risks of a POEM or G-POEM include:

  • Sore throat from having the endoscope inserted into your mouth

  • Inflammation of the esophagus

  • Infection

  • Bleeding 

  • Gastroesophageal reflux disease (GERD)

  • Collapsed lung

  • Air bubble in the space between the lungs

You may also experience some side effects from the anesthesia you receive such as nausea, vomiting, headache, and dizziness.

Contact Us

To learn more about peroral endoscopic myotomy or to make an appointment, please call 800.8.COOPER (800.826.6737).

Refer a Patient

If you are a doctor who wants to refer a patient for a peroral endoscopic myotomy, please call 800.8.COOPER (800.826.6737).